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Choose from our wide selection of French homes for your ideal Indre-et-Loire holiday rental house, gite, villa or apartment. Indre-et-Loire is a department in west-central France named after the Indre and the Loire rivers. The Indre-et-Loire department of France is the most westerly of the departments in the Centre (Val de Loire) region of central France, and a very popular destination with visitors from both France and oevrseas.